HPV Cancer Statistics

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HPV, cancer statisticsEvery year, over 30,000 new cases of cancer directly related to HPV infection are diagnosed in the United States. 

These cancers include cervical, throat, penile, anal, rectal, vaginal and vulvar cancers.

In comparison, over 210,000 cases of lung cancer are diagnosed in the United States every year (1).

Cervical Cancer

Diagnosed in 11,770 women annually, cervical cancer is one of the most common types of cancer directly linked to an HPV infection.

91% cases have been attributed to HPV infection (2)

66% of these cancers are caused by HPV types 16 and 18

15% are due to infection with HPV types 31, 33, 45, 52, 58

Pap Smear

Cervical cancer is one of only a handful of cancers for which there exists a fairly dependable and simple screening test, a Pap smear.

Cells collected for a Pap smear, may also be examined for the presence of HPV, which will add to the value of the final test result.

Pap smear is recommended for all women between the ages of 21 and 65. 

The frequency of Pap smear screening depends on the results of the previous test.

Women with normal results are typically urged to repeat their Pap smear in 2-3 years.

Pap smear does not screen against other types of cancer, such as ovarian, vaginal or vulvar cancers.

Throat Cancer

Also referred to as Oropharyngeal cancer.

Very common type of cancer with nearly 70% cases directly linked to HPV infection.

Diagnosed in 15,700 individuals annually. Of these, 11,000 cases are caused by HPV.

HPV types 16 and 18 are linked to about 60% cases.

Males are affected nearly 4 times more commonly than women.

Classically attributed to alcohol and tobacco use, throat cancer due to HPV infection is becoming increasingly common (3).

Oral HPV infection has been found in up to 16% of partners of individuals diagnosed with throat cancer (4).

Screening for throat cancer is not recommended.

Anal Cancer

Diagnosed in 5,000 individuals annually. 

About 90% of these cases are directly linked to HPV in both men and women.

HPV types 16 and 18 are the main culprit in 79% cases.

HPV types 31, 33, 45, 52, 58 have been linked to only 8% cases of anal cancer.

Women are affected nearly twice as often as men.

Although currently there are no recommendations for anal Pap test to screen for anal cancer.  Some healthcare providers offer anal cancer screening for men with immune system disorders and those who receive anal sex.

Penile Cancer

Diagnosed on average in 1,168 men every year with some 60% cases attributed to HPV infection.

HPV types 16 and 18 have been linked to about half of these cancers.

HPV types 31, 33, 45, 52, 58 likely cause 9% of cancer of the penis.

Most common types of penile cancer associated with HPV include Basal and squamous cell carcinoma (5).

Screening for the cancer of penis is not recommended.

Factors that increased the risk of penile cancer, include: uncircumcised status, anal warts and phimosis.

Rectal Cancer

Diagnosed in 750 individuals annually.

Women are slightly more likely to become affected than men.

91% cases of rectal cancer are attributed to HPV infection.

HPV types 16 and 18 have been linked to 91% cases of rectal cancer.

HPV types 31, 33, 45, 52, 58 only cause 8% of rectal cancer.

Vaginal Cancer

Diagnosed in 800 women annually.

75% cases are due to HPV.

Of these vaginal cancers caused by HPV infection, 55% are attributed to HPV types 16 and 18, while 18% are likely caused by HPV types 31, 33, 45, 52, 58.

Vulvar Cancer

Vulvar cancer is diagnosed in about 3,550 American women every year.

69% of cases are linked to an HPV infection.

HPV types 16 and 18 have been linked to about 55% of these cancers.

HPV types 31, 33, 45, 52, 58 are associated with only 14% cases of vulvar cancer.

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cases of Cervical Cancer due to HPV

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cases of Throat Cancer due to HPV

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cases of Vaginal Cancer due to HPV

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